HBOC - Fabric Genomics

Fabric Hx for Cancer: Breast & Ovarian

Turnkey sample-to-report hereditary breast and ovarian cancer testing solution that will enable any laboratory to deliver high quality clinical reporting confidently and cost effectively

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Next Generation Sequencing (NGS) testing is crucial for breast & ovarian cancer care

  • Streamlined Implementation & Operations
    Integrated workflow solution including lab set up and validation plan, AI interpretation and reporting tools, and orthogonal testing options
  • High Accuracy You & Your Patients Can Trust
    Short-read sequencing solutions that deliver the highest levels of accuracy for both single nucleotide variations (SNVs) and structural variations (SVs; also referred to as copy number deletion/duplication events)
  • Designed for Cost Effectiveness
    Right set of genes based on clinical value and ability to operationalize most efficiently

Streamlined Implementation & Operations

  • Optimized lab set up and validation protocol to get started quickly and efficiently
  • Built-in, best-in-class AI interpretation and reporting tools
  • Integrated workflow allows orthogonal solution for structural variants

* Positive samples can be sent out for confirmatory testing

High Accuracy You & Your Patients Can Trust

  • >99.98% sensitivity for SNVs and indels
  • >99.9% specificity for SNVs, indels, and SVs
  • >97% sensitivity for long and short CNVs (SVs)

Structural Variant Detection—BRCA1: Long CNV caller is optimized for detecting large deletion events such as >2 KB and Short CNV caller for events starting at single exon level.

Designed for Cost Effectiveness

  • Covers all genes recommended by NCCN Guidelines
  • Consistent coverage of genes with top send-out labs
  • Cost-effective solution with high accuracy and faster average TAT

BRCA1 (BRCA1, DNA repair associated), BRCA2 (BRCA2, DNA repair associated) (e.g., hereditary breast and ovarian cancer) CPT code requires; full sequence analysis and full duplication/deletion analysis (i.e., detection of gene rearrangements and CNVs)

Assumes 10% reflex rate for positive samples

Fabric is the leader in NGS testing and clinical interpretation

 

Ready for turnkey sample-to-report hereditary breast and ovarian cancer risk reporting?

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