Why Fabric

Fabric’s vision is to transform healthcare through AI-driven clinical genomic insights that improve patient lives. Fabric Genomics enables hospitals and labs to achieve the highest diagnostic yield and fastest turnaround of any genomic analysis platform.

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Key Benefits

Pioneered AI-Driven Genomic Interpretation

Starting in 2011 with VAAST (Yandell et al, Genome Research), expanding with Phevor in 2014 (Singleton et al, AJHG) and VVP in 2018 (Flygare et al, BMC Bioinf.), Fabric Genomics has been analyzing and interpreting complex genomic data using AI-based approaches to accurately prioritize the most phenotypically relevant variants.


Single Platform to Accelerate NGS Diagnostic Testing

Fabric Enterprise was designed to support all NGS-based diagnostic tests regardless of test type or scale. Starting from either raw data or variant calls, from whole genome, exome, or panel tests, the Fabric platform provides efficient workflows for annotating, interpreting, report generation, and sign-off.


Increased Diagnostic Yield

Our VAAST+Phevor algorithms have been shown to identify the causative variant as the #1 candidate in roughly half of returned rare disease cases at Genomics England (1,973 cases returned to date) and are currently powering candidate variant yields of up to 49.8% – compared to an industry-average of 25-30%.


Secure and Regulatory Compliant

Our cloud and on-site hosting options incorporate comprehensive data and network security protocols. Fabric maintains compliance programs for HIPAA, ISO 27001, FDA 21 CFR part 11 and Part 820, and CLIA and CAP regulations.

Case Studies

Discover how Fabric Genomics can help your lab succeed with NGS testing using our automated platform for analysis and interpretation