Streamlined whole genome analysis for hereditary
rare disease
Turn diagnostic odysseys into answers with Fabric GEM, the world's fastest end-to-end WGS/WES interpretation pipeline
Solve your most important difficult applications
Rare and Undiagnosed Diseases
Ultra-rapid NICU & PICU cases
Re-analysis of negative cases
Solos and nuclear families
Efficient data analysis
For childhood diseases and time-sensitive medical conditions, reducing the time to diagnosis can significantly improve outcomes and quality life.
Fabric GEM allows you to interpret whole genomes in ~15 minutes and prioritizes high-value diagnostic candidates, so you can focus your attention on a smaller number of high-value candidate genes.Â
Average number of genes to achieve 90% diagnosis rate
Best in class accuracy
1st or 2nd candidate*
top 5 list*
top 10 list*
*data from Fabric GEM validation at Rady Children’s Institute for Genomic Medicine
+Fabric AI VAAST and Phevor, data from UK 100,000 Genomes Project as reported at ESHG 2018
Sign-out more cases/day
Fabric GEM enables an unprecedented level of
automation, speed and accuracy, breaking the
interpretation bottleneck in clinical workflows.
In a validation dataset at Rady Children’s Institute
for Genomic Medicine, Fabric GEM reduced clinical review by >90%, enabling 10x more cases with the same team.
See more details about the impact of Fabric GEM at Rady’s Children’s Institute for Genomic Medicine
Better Knowledge Synthesis for Difficult Cases
Fabric GEM leverages genomic, phenotypic, and clinical data to achieve extreme sensitivity
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