Fabric Hereditary Panels with ACE
Data Sheet

Fabric Hereditary Panels with ACE

A New Solution for Newborn Screening

Introducing a new solution for variant interpretation and clinical reporting: Fabric Hereditary Panels powered by ACE (AI Classification Engine). Leverage an extensively validated, automated ACMG classification engine to accelerate accurate variant interpretation, classification, and clinical reporting down to minutes per case. 

Increase Accuracy and Turnaround Time for Newborn Screening

 ACE is Fabric’s new AI-based inference engine that leverages deep gene and variant annotation for highly accurate ACMG variant classification. ACE is embedded into Fabric Enterprise for a complete FASTQ-to-clinical report workflow and is now available for newborn screening. 

Fabric Enterprise enables hospitals and labs to achieve the highest-accuracy clinical interpretation and fastest turnaround of any genomic analysis platform. With its accurate alignment and variant calling, up-to-date variant annotation, and configurable SOP-based workflows, it strengthens labs’ processes with a best-in-class bioinformatics pipeline. ACE makes ACMG classification fast and easy, reducing VUS backlogs and growing your lab’s classified variant database with each approved clinical report. 

Fabric Enterprise is a secure, cloud-based application. Fabric Genomics maintains HIPAA, ISO 27001, CAP, and CLIA compliance programs.

 

Fabric Hereditary Panels powered by ACE (AI Classification Engine) 

Accurate

Increase confidence in your results with ACMG-compliant classification backed by validation across thousands of variants. 

Rapid 

Accelerate turnaround time from sequence to report down to minutes per case. 

Scalable 

Remove interpretation bottlenecks to enable more scale while reducing personnel costs. 

The Newborn Screening Panel includes 30 genes to screen for serious health conditions at birth
ALDOB
ALPL
ARSA
ARSB
ASAH1
ATP7A
COL3A1
CTNS
CYP27A1
DHCR7
DMD
G6PD
GAA
GALC
GAMT
GBA
GJB2
GLA
GUSB
IDS
IDUA
LIPA
MAN2B1
NAGLU
RB1
SGSH
SLC7A7
SMN1
SMPD1
TPP1